Recombinant human CAB39 protein

Calcium binding protein 39, also known as CAB39, is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. Also CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization. Recombinant human CAB39, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Calcium binding protein 39, CGI-66, MO25, Calcium binding protein 39, CAB 39, CAB-39, MO 25, MO-25, FLJ22682

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

42 kDa (361aa) confirmed by MALDI-TOF

Additionnal Information

CAB39, Calcium binding protein 39, CGI-66, MO25, Calcium binding protein 39, CAB 39, CAB-39, MO 25, MO-25, FLJ22682, ATGP0617-10 µg, ATGP0617-20 µg, ATGP0617-50 µg, ATGP0617-100 µg, ATGP0617-250 µg, ATGP0617-500 µg, ATGP0617-1 mg, ATGP0617-10, ATGP0617-20, ATGP0617-50, ATGP0617-100, ATGP0617-250, ATGP0617-500, ATGP0617-1

References & Citations

Baas AF., et al. (2004) Trends Cell Biol. 14 (6) :312-9.; ; Boudeau J., et al. (2003) EMBO J. 22 (19) :5102-14.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_057373

Uniprot Accession Number

Q9Y376

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MPFPFGKSHK SPADIVKNLK ESMAVLEKQD ISDKKAEKAT EEVSKNLVAM KEILYGTNEK EPQTEAVAQL AQELYNSGLL STLVADLQLI DFEGKKDVAQ IFNNILRRQI GTRTPTVEYI CTQQNILFML LKGYESPEIA LNCGIMLREC IRHEPLAKII LWSEQFYDFF RYVEMSTFDI ASDAFATFKD LLTRHKLLSA EFLEQHYDRF FSEYEKLLHS ENYVTKRQSL KLLGELLLDR HNFTIMTKYI SKPENLKLMM NLLRDKSRNI QFEAFHVFKV FVANPNKTQP ILDILLKNQA KLIEFLSKFQ NDRTEDEQFN DEKTYLVKQI RDLKRPAQQE A