Recombinant human ACADM protein

ACADM, also known as acyl-Coenzyme A dehydrogenase is an enzyme that is important for breaking down (degrading) a certain group of fats called medium-chain fatty acids. It is essential for converting these particular fatty acids to energy, especially during periods without food (fasting) . This protein functions in mitochondria, the energy-producing centers within cells. It is found in the mitochondria of several types of tissues, particularly the liver. Recombinant human ACADM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Medium-chain specific acyl-CoA dehydrogenase, ACAD1, CAD, MCADH, Medium-chain specific acyl-CoA dehydrogenase, ACAD 1, Acyl Coenzyme A Dehydrogenase, Acyl coenzyme A dehydrogenase C 4 to C 12 straight chain, C4 to C12 Straight Chain, FLJ18227, FLJ93013, FLJ99884, MCAD, Medium chain acyl CoA dehydrogenase, Medium chain fatty acyl CoA dehydrogenase, Medium chain specific acyl CoA dehydrogenase, Medium chain specific acyl CoA dehydrogenase mitochondrial

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

45.9 kDa (417aa) confirmed by MALDI-TOF

Additionnal Information

ACADM, Medium-chain specific acyl-CoA dehydrogenase, ACAD1, CAD, MCADH, Medium-chain specific acyl-CoA dehydrogenase, ACAD 1, Acyl Coenzyme A Dehydrogenase, Acyl coenzyme A dehydrogenase C 4 to C 12 straight chain, C4 to C12 Straight Chain, FLJ18227, FLJ93013, FLJ99884, MCAD, Medium chain acyl CoA dehydrogenase, Medium chain fatty acyl CoA dehydrogenase, Medium chain specific acyl CoA dehydrogenase, Medium chain specific acyl CoA dehydrogenase mitochondrial, ATGP0603-10 µg, ATGP0603-20 µg, ATGP0603-50 µg, ATGP0603-100 µg, ATGP0603-250 µg, ATGP0603-500 µg, ATGP0603-1 mg, ATGP0603-10, ATGP0603-20, ATGP0603-50, ATGP0603-100, ATGP0603-250, ATGP0603-500, ATGP0603-1

References & Citations

Gregersen N., et al. (2001) Hum Mutat. 18 (3) :169-89.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.1M NaCl

Scientific Category

Enzymes & Proteases

NCBI Accession Number

NP_000007

Uniprot Accession Number

P11310

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MKANRQREPG LGFSFEFTEQ QKEFQATARK FAREEIIPVA AEYDKTGEYP VPLIRRAWEL GLMNTHIPEN CGGLGLGTFD ACLISEELAY GCTGVQTAIE GNSLGQMPII IAGNDQQKKK YLGRMTEEPL MCAYCVTEPG AGSDVAGIKT KAEKKGDEYI INGQKMWITN GGKANWYFLL ARSDPDPKAP ANKAFTGFIV EADTPGIQIG RKELNMGQRC SDTRGIVFED VKVPKENVLI GDGAGFKVAM GAFDKTRPVV AAGAVGLAQR ALDEATKYAL ERKTFGKLLV EHQAISFMLA EMAMKVELAR MSYQRAAWEV DSGRRNTYYA SIAKAFAGDI ANQLATDAVQ ILGGNGFNTE YPVEKLMRDA KIYQIYEGTS QIQRLIVARE HIDKYKN