Recombinant human Cytoglobin/CYGB protein

CYGB is a globin molecule located in the brain and most notably utilized in marine mammals. It is thought to be a method of protection under conditions of hypoxia. The predicted function of cytoglobin is the modulation of oxygen and nitric oxide metabolism or scavenging free radicals within a cell. Recombinant human CYGB, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

CYGB, Cytoglobin, HGB, Histoglobin, STAP, Stellate cell activation associated protein

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

23.5 kDa (210aa) confirmed by MALDI-TOF

Additionnal Information

CYGB, Cytoglobin, HGB, STAP, Cytoglobin, CYGB, Histoglobin, Stellate cell activation associated protein., ATGP0592-10 µg, ATGP0592-20 µg, ATGP0592-50 µg, ATGP0592-100 µg, ATGP0592-250 µg, ATGP0592-500 µg, ATGP0592-1 mg, ATGP0592-10, ATGP0592-20, ATGP0592-50, ATGP0592-100, ATGP0592-250, ATGP0592-500, ATGP0592-1

References & Citations

Hankeln T., et al. (2002) Mol Biol Evol. 19 (4) :416-21; ; Gazdar AF., et al. (2008) Cancer Res. 68 (18) :7448-56;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Redox Proteins

NCBI Accession Number

AAH29798

Uniprot Accession Number

Q8WWM9

Species

Human

AA Sequence

MEKVPGEMEI ERRERSEELS EAERKAVQAM WARLYASCED VGVAILVRFF VNFPSAKQYF SQFKHMEDPL EMERSPQLRK HACRVMGALN TVVENLHDPD KVSSVLALVG KAHALKHKVE PVYFKILSGV ILEVVAEEFA SDFPPETQRA WAKLRGLIYS HVTAAYKEVG WVQQVPNATT PPATLPSSGP