What is the catalog number for Recombinant human SORD protein?

The catalog number for Recombinant human SORD protein is ATGP0574-100.

What sizes are available for Recombinant human SORD protein?

Recombinant human SORD protein is available in the following size(s): 100 µg.

Is Recombinant human SORD protein in stock?

Recombinant human SORD protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human SORD protein

SORD, also known as L-iditol 2-dehydrogenase or SORD1, is a 357 amino acid member of the zinc-containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney and in the lens of the eye. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses. Recombinant human SORD protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Specific activity is > 20,000 pmol/min/ug, and is defined as the amount of enzyme that catalyze D-fructose to D-sorbitol per minute at pH 7.5 at 37C.

Product Name Alternative

Sorbitol dehydrogenase, Sorbitol dehydrogenase L iditol 2 dehydrogenase, SDH, SORD, SORD 1, SORD1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

Enzyme Activity, SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Bioactivity

Specific activity is > 20,000pmol/min/ug, and is defined as the amount of enzyme that catalyze D-fructose to D-sorbitol per minute at pH 7.5 at 37C.

Molecular Weight

40.4 kDa (377aa) confirmed by MALDI-TOF

Additionnal Information

SORD, Sorbitol dehydrogenase, Sorbitol dehydrogenase L iditol 2 dehydrogenase, SDH, SORD, SORD 1, SORD1, ATGP0574-10 µg, ATGP0574-20 µg, ATGP0574-50 µg, ATGP0574-100 µg, ATGP0574-250 µg, ATGP0574-500 µg, ATGP0574-1 mg, ATGP0574-10, ATGP0574-20, ATGP0574-50, ATGP0574-100, ATGP0574-250, ATGP0574-500, ATGP0574-1

References & Citations

Baker MA., et al. (2010) Proteomics. 10 (3) :482-95. ; ; Sorger D., et al. (2009) Nucl Med Biol. 36 (1) :17-27.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol

Scientific Category

Metabolism

NCBI Accession Number

AAH25295

Uniprot Accession Number

Q00796

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP