Recombinant human SUB1 protein

SuB1, also known as PC4, is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. SuB1 interacts with the activation domain of transcription factor IIA (TFIIA) and TATA-binding protein (TBP) -associated factors (TAFs) to directly bind to double stranded DNA. This protein induces both activation and repression of RNAPII basal transcription, depending on the presence or absence of these transcription factors and holoenzyme components. Recombinant human SuB1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

SUB1 regulator of transcriptio, SUB1 homolog transcriptional regulator, Activated RNA polymerase II transcriptional coactivator p15, Positive cofactor 4, PC4, SUB1 homolog, p14, PC4, RPO2TC1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

16.5 kDa (147aa) confirmed by MALDI-TOF

Additionnal Information

SuB1, Activated RNA polymerase II transcriptional coactivator p15, p14, P15, PC4, Activated RNA polymerase II transcriptional coactivator p15 Activated RNA polymerase II transcriptional coactivator p15, Interferon related developmental regulator 1, MGC102747, PC4 LSB, Positive cofactor 4, RPO2TC1, SuB1, SuB1 homolog., ATGP0573-10 µg, ATGP0573-20 µg, ATGP0573-50 µg, ATGP0573-100 µg, ATGP0573-250 µg, ATGP0573-500 µg, ATGP0573-1 mg, ATGP0573-10, ATGP0573-20, ATGP0573-50, ATGP0573-100, ATGP0573-250, ATGP0573-500, ATGP0573-1