Recombinant human PIG3/TP53I3 protein
TP53I3, also known as quinone oxidoreductase PIG3, is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. It is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. This protein has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Recombinant human TP53I3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Quinone oxidoreductase PIG3, NADPH:quinone reductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.6 kDa (352aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Flatt PM. et al. (2000) Cancer Lett. 156 (1) :63-72.; ; Porte S, et al. (2009) J Biol Chem.. 284 (25) :17194-205;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_671713
Uniprot Accession Number
Q53FA7
Species
Human
AA Sequence
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