Recombinant human TRAF-1 protein

TRAF1, also known as TNF receptor-associated factor 1, belongs to TNF receptor superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The complex also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. Recombinant human TRAF1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

TNF receptor-associated factor 1, EBI6, TNF receptor-associated factor 1 4732496E14Rik, EBV induced protein 6, Epstein-Barr virus-induced protein 6, Tnf receptor associated factor 1, TRAF 1.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

19.5 kDa (172aa) confirmed by MALDI-TOF

Additionnal Information

TRAF1, TNF receptor-associated factor 1, EBI6, TNF receptor-associated factor 1 4732496E14Rik, EBV induced protein 6, Epstein-Barr virus-induced protein 6, Tnf receptor associated factor 1, TRAF 1., ATGP0571-10 µg, ATGP0571-20 µg, ATGP0571-50 µg, ATGP0571-100 µg, ATGP0571-250 µg, ATGP0571-500 µg, ATGP0571-1 mg, ATGP0571-10, ATGP0571-20, ATGP0571-50, ATGP0571-100, ATGP0571-250, ATGP0571-500, ATGP0571-1

References & Citations

Ansieau S. et al. (1996) Proc Natl Acad Sci u S A. 93 (24) :14053-8.; ; Leo E, et al. (2001) J Biol Chem. 276 (11) :8087-93;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Apoptosis

NCBI Accession Number

NP_005649

Uniprot Accession Number

Q13077

Species

Human

AA Sequence

MDGTFLWKIT NVTRRCHESA CGRTVSLFSP AFYTAKYGYK LCLRLYLNGD GTGKRTHLSL FIVIMRGEYD ALLPWPFRNK VTFMLLDQNN REHAIDAFRP DLSSASFQRP QSETNVASGC PLFFPLSKLQ SPKHAYVKDD TMFLKCIVET ST