Recombinant human GADD45 alpha protein

GADD45A, also known as growth arrest and DNA damage-inducible protein, binds both Cdks and PCNA, a protein involved in DNA replication and repair. It has been shown to stimulate DNA excision repair in vitro and to inhibit entry of cells into S phase. This protein may serve as a link between p53-dependent cell cycle checkpoint and DNA repair. Recombinant human GADD45A protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Growth arrest and DNA damage-inducible protein GADD45 alpha, DDIT1, GADD45, Growth arrest and DNA damage-inducible protein GADD45 alpha DDIT 1, DNA damage inducible transcript 1, Growth arrest and DNA damage inducible 45 alpha

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

19.4 kDa (173aa) confirmed by MALDI-TOF

Additionnal Information

GADD45 a, Growth arrest and DNA damage-inducible protein GADD45 alpha, DDIT1, GADD45, Growth arrest and DNA damage-inducible protein GADD45 alpha DDIT 1, DNA damage inducible transcript 1, Growth arrest and DNA damage inducible 45 alpha, ATGP0548-10 µg, ATGP0548-20 µg, ATGP0548-50 µg, ATGP0548-100 µg, ATGP0548-250 µg, ATGP0548-500 µg, ATGP0548-1 mg, ATGP0548-10, ATGP0548-20, ATGP0548-50, ATGP0548-100, ATGP0548-250, ATGP0548-500, ATGP0548-1