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Recombinant human Max protein

MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. In contrast to Myc, which is highly regulated during progression through the cell cycle, Max is highly stable and is much more abundant than Myc. Recombinant human MAX protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Protein max, Myc-associated factor X, Class D basic helix-loop-helix protein 4, bHLHd4, BHLHD4, bHLHd5, bHLHd6, bHLHd7, bHLHd8

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19.3 kDa (168aa) confirmed by MALDI-TOF

Additionnal Information

MAX, MYC associated factor X, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, MYC associated factor X Helix loop helix zipper protein, MAX protein, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, Myc associated factor X, Myc binding novel HLH/LZ protein, Orf 1, Orf1, Protein max., ATGP0539-10 µg, ATGP0539-20 µg, ATGP0539-50 µg, ATGP0539-100 µg, ATGP0539-250 µg, ATGP0539-500 µg, ATGP0539-1 mg, ATGP0539-10, ATGP0539-20, ATGP0539-50, ATGP0539-100, ATGP0539-250, ATGP0539-500, ATGP0539-1

References & Citations

Burbano HA., et al. (2010) Science. 328 (5979) :723-5.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_002373.3

Uniprot Accession Number

P61244

Species

Human

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