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Recombinant human CCL27/CTACK protein

Cutaneous T cell-attracting chemokine CCL27 is a member of the chemokine superfamily and the subfamily of beta r C-C chemokines that binds chemokine receptor CCR10. Chemokines are a superfamily of small secreted proteins that attract their targets by interacting with G protein-coupled receptors expressed on the migrating cell. CCL27 is involved in the preferential migration and recruitment of cutaneous lymphocyte-associated antigen CLA+ memory lymphocytes. Recombinant human CCL27 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

C-C motif chemokine ligand 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, Eskine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27, SCYA27, ALP, ILC, ESKY, CTAK

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

10.2 kDa (89aa) confirmed by MALDI-TOF

Additionnal Information

CCL27, CTACK, C-C motif chemokine 27, ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27, C-C motif chemokine 27 CC chemokine ILC, Cutaneous T cell attracting chemokine, Eskine, IL 11 R alpha locus chemokine, Skinkine, Small inducible cytokine A27, ATGP0520-10 µg, ATGP0520-20 µg, ATGP0520-50 µg, ATGP0520-100 µg, ATGP0520-250 µg, ATGP0520-500 µg, ATGP0520-1 mg, ATGP0520-10, ATGP0520-20, ATGP0520-50, ATGP0520-100, ATGP0520-250, ATGP0520-500, ATGP0520-1

References & Citations

Homey B., et al. (2002) Nat Med. 8 (2) :157-65. ; ; Kanda N., et al. (2007) Clin Exp Allergy. 37 (7) :1074-82.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_006655.1

Uniprot Accession Number

Q9Y4X3

Species

Human

AA Sequence

MFLLPPSTAC CTQLYRKPLS DKLLRKVIQV ELQEADGDCH LQAFVLHLAQ RSICIHPQNP SLSQWFEHQE RKLHGTLPKL NFGMLRKMG

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