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Recombinant human HMGN1 protein

HMGN1, also known as non-histone chromosomal protein HMG-14, belongs to the HMGN family. Chromosomal protein HMGN1 binds to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. This protein may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Recombinant human HMGN1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Non-histone chromosomal protein HMG-14, HMG14, GC104230, Non-histone chromosomal protein HMG-14 FLJ27265, FLJ31471, High mobility group (nonhistone chromosomal) protein 14, High mobility group nucleosome binding 1, High mobility group nucleosome binding domain 1, High mobility group nucleosome binding domain containing protein 1, High mobility group protein 14, HMG 14 HMGN 1, HMGN1, MGC104230, MGC117425, Nonhistone chromosomal protein HMG 14, Nonhistone chromosomal protein HMG14.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by BCA assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

11.7 kDa (108aa) confirmed by MALDI-TOF

Additionnal Information

HMGN1, Non-histone chromosomal protein HMG-14, HMG14, GC104230, Non-histone chromosomal protein HMG-14 FLJ27265, FLJ31471, High mobility group (nonhistone chromosomal) protein 14, High mobility group nucleosome binding 1, High mobility group nucleosome binding domain 1, High mobility group nucleosome binding domain containing protein 1, High mobility group protein 14, HMG 14 HMGN 1, HMGN1, MGC104230, MGC117425, Nonhistone chromosomal protein HMG 14, Nonhistone chromosomal protein HMG14., ATGP0515-10 µg, ATGP0515-20 µg, ATGP0515-50 µg, ATGP0515-100 µg, ATGP0515-250 µg, ATGP0515-500 µg, ATGP0515-1 mg, ATGP0515-10, ATGP0515-20, ATGP0515-50, ATGP0515-100, ATGP0515-250, ATGP0515-500, ATGP0515-1

References & Citations

Landsman D. et al, (1989) J Biol Chem. 264 (6) :3421-7

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 0.1mM PMSF

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_004956.5

Uniprot Accession Number

P05114

Species

Human

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