Recombinant human HMGN1 protein
HMGN1, also known as non-histone chromosomal protein HMG-14, belongs to the HMGN family. Chromosomal protein HMGN1 binds to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. This protein may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Recombinant human HMGN1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by BCA assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
11.7 kDa (108aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Landsman D. et al, (1989) J Biol Chem. 264 (6) :3421-7
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 0.1mM PMSF
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_004956.5
Uniprot Accession Number
P05114
Species
Human
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