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Recombinant human SOX2 protein

SRY (sex determining region Y) -box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. This Protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Recombinant human SOX2 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

SRY (sex determining region Y) -box 2, ANOP3, MCOPS3, MGC2413, SRY (sex determining region Y) -box 2 ANOP3, cb236, Delta EF2a, lcc, MGC148683, RGD1565646, Sex determining region Y box 2, SOX 2, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box 2, Transcription factor SOX 2, ysb.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

23.1 kDa (208aa) confirmed by MALDI-TOF

Additionnal Information

SOX2, SRY (sex determining region Y) -box 2, ANOP3, MCOPS3, MGC2413, SRY (sex determining region Y) -box 2 ANOP3, cb236, Delta EF2a, lcc, MGC148683, RGD1565646, Sex determining region Y box 2, SOX 2, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box 2, Transcription factor SOX 2, ysb., ATGP0514-10 µg, ATGP0514-20 µg, ATGP0514-50 µg, ATGP0514-100 µg, ATGP0514-250 µg, ATGP0514-500 µg, ATGP0514-1 mg, ATGP0514-10, ATGP0514-20, ATGP0514-50, ATGP0514-100, ATGP0514-250, ATGP0514-500, ATGP0514-1

References & Citations

Wei Z., et al. (2009) Stem Cells. 27 (12) :2969-78.; ; Martinez-Fernandez A., et al. (2009) Circ Res. 25 105 (7) :648-56.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 200 mM NaCl, 2mM DTT, 40% Glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_003097.1

Uniprot Accession Number

P48431

Species

Human

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