Recombinant human SOX2 protein
SRY (sex determining region Y) -box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. This Protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Recombinant human SOX2 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.1 kDa (208aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wei Z., et al. (2009) Stem Cells. 27 (12) :2969-78.; ; Martinez-Fernandez A., et al. (2009) Circ Res. 25 105 (7) :648-56.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 200 mM NaCl, 2mM DTT, 40% Glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_003097.1
Uniprot Accession Number
P48431
Species
Human
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