Recombinant human Sulfotransferase 2B1/SULT2B1 protein

Sulfotransferase family cytosolic 2B member 1 isoform b, also known as SuLT2B1, is a member of Sulfotransferase family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SuLT2B1b is localized in the cytosol and nuclei of human cells. SuLT2B1b is selective for the sulfation of 3beta-hydroxysteroids such as dehydroepiandrosterone and pregnenolone, and may also have a role in cholesterol sulfation in human skin. Recombinant human SuLT2B1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Sulfotransferase family 2B member 1, Sulfotransferase 2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family cytosolic 2B member 1, ST2B1, HSST2

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

41.3 kDa (365aa) confirmed by MALDI-TOF

Additionnal Information

Cytosolic Sulfotransferase2B1, SULT2B1, Sulfotransferase family cytosolic 2B member 1 isoform b, HSST2, ST2B1, Sulfotransferase family cytosolic 2B member 1 isoform b Alcohol sulfotransferase, EC 2.8.2.2, Hydroxysteroid sulfotransferase 2, Sulfotransferase 2B1, Sulfotransferase family cytosolic 2B member 1, SuLT2B1a, SuLT2B1b., ATGP0510-10 µg, ATGP0510-20 µg, ATGP0510-50 µg, ATGP0510-100 µg, ATGP0510-250 µg, ATGP0510-500 µg, ATGP0510-1 mg, ATGP0510-10, ATGP0510-20, ATGP0510-50, ATGP0510-100, ATGP0510-250, ATGP0510-500, ATGP0510-1

References & Citations

Dumas NA., et al. (2008) J Steroid Biochem Mol Biol. 111:171-7. ; ; He D., et al. (2005) Biolchim Biophys Acta. 1724:11-26.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_814444

Uniprot Accession Number

O00204

Species

Human

AA Sequence

MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS LAENTQDVRD DDIFIITYPK SGTTWMIEII CLILKEGDPS WIRSVPIWER APWCETIVGA FSLPDQYSPR LMSSHLPIQI FTKAFFSSKA KVIYMGRNPR DVVVSLYHYS KIAGQLKDPG TPDQFLRDFL KGEVQFGSWF DHIKGWLRMK GKDNFLFITY EELQQDLQGS VERICGFLGR PLGKEALGSV VAHSTFSAMK ANTMSNYTLL PPSLLDHRRG AFLRKGVCGD WKNHFTVAQS EAFDRAYRKQ MRGMPTFPWD EDPEEDGSPD PEPSPEPEPK PSLEPNTSLE REPRPNSSPS PSPGQASETP HPRPS