Recombinant human Calsequestrin 2/CASQ2 protein
Calsequestrin2 is a calcium-binding protein of the sarcoplasmic reticulum. The protein helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. It also helps sarcoplasmic reticulum store an amazing amount of calcium ions. Recombinant Calsequestrin2 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Cardiac muscle calsequestrin 2, PDIB2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
48.4 kDa (417aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wang S, et al. (1998) Nat. Struct. Biol.. 5 (6) :476-83.; ; Lahat H, et al. (2001) Am J Hum Genet. 69 (6) :1378-84.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001223
Uniprot Accession Number
O14958
Species
Human
AA Sequence
Frequently Asked Questions
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