Recombinant human DHPS protein
DHPS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. This protein catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. Recombinant DHPS protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Deoxyhypusine synthase, MIG13, Deoxyhypusine synthase DHS, DS, Migration inducing gene 13.
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
43.1 kDa (389aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Umland TC, et al. (2004) J. Biol. Chem. 279 (27) : 28697-705; ; Jones T, et al. (1996) Genomics. 35 (3) : 635-7.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_001921.1
Uniprot Accession Number
P49366
Species
Human
AA Sequence
Frequently Asked Questions
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