Recombinant human Glutathione S-transferase zeta 1/GSTZ1 protein

GSTZ1, also known as maleylacetoacetate isomerase, is an enzyme that belongs to glutathione S-transferase (GSTs) super-family. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur) . The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. It also plays a significant role in the catabolism of phenylalanine and tyrosine. Recombinant GSTZ1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Glutathione S-transferase zeta 1, GSTZ1-1, MAAI, MAI, Glutathione S-transferase zeta 1 EC 2.5.1.18, EC 5.2.1.2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

26.2 kDa (236aa) confirmed by MALDI-TOF

Additionnal Information

MAI, MAAI, GSTZ1-1, GSTZ1, Glutathione S-Transferase Zeta-1, Glutathione S-transferase zeta1, Glutathione S-transferase zeta 1 EC 2.5.1.18, Glutathione S-transferase zeta 1, Glutathione S transferase zeta1, Glutathione S transferase zeta 1 EC 2.5.1.18, Glutathione S transferase zeta 1, EC 5.2.1.2, GSTZ1 1, ATGP0491-10 µg, ATGP0491-20 µg, ATGP0491-50 µg, ATGP0491-100 µg, ATGP0491-250 µg, ATGP0491-500 µg, ATGP0491-1 mg, ATGP0491-010, ATGP0491-020, ATGP0491-050, ATGP0491-100, ATGP0491-250, ATGP0491-500, ATGP0491-01M

References & Citations

Board PG, et al. (1997) Biochem J. 328:929-35.; ; Fernandez-Canon JM., et al. (1998) J Biol Chem. 273 (1) :329-37;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

AAC33591

Uniprot Accession Number

O43708

Species

Human

AA Sequence

MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE ETRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA