Recombinant human VAP-A protein
VAPA is a type IV membrane protein, present in the plasma membrane, intracellular vesicles and may also be associated with the cytoskeleton. This protein is a SNARE regulator with high levels of expression in the intestine during late embryogenesis and early neonatal development. VAPA may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Recombinant VAPA protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
29.8 kDa (264aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wyles JP., et al. (2002) J Biol Chem. 277 (33) :29908-18. ; ; Weir ML., et al. (2001) Biochem Biophys Res Commun. 286 (3) :616-21.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Scientific Category
Adhesion & Movement
NCBI Accession Number
NP_919415
Uniprot Accession Number
Q9P0L0
Species
Human
AA Sequence
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