Recombinant human Syndecan-4/SDC4 protein
Syndecan 4 belongs to syndecan proteoglycan family (type I integral membrane proteoglycans) that are involved in cell-extracellular matrix adhesion and growth factor binding. This protein functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly. It is also a transmembrane protein specifically enriched in Schwann cell perinodal processes. Recombinant Syndecan 4 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Syndecan 4, Amphiglycan, Ryudocan, SYND4 , Syndecan proteoglycan 4, Ryudocan core protein
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
13.9 kDa (128aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Bass MD., et al. (2002) Biochem J.. 368 :1-15; ; Woods A., et al. (1994) Mol Biol Cell. 5 (2) :183-92.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_002990
Uniprot Accession Number
P31431
Species
Human
AA Sequence
MESIRETEVI DPQDLLEGRY FSGALPDDED VVGPGQESDD FELSGSGDLD DLEDSMIGPE VVHPLVPLDN HIPERAGSGS QVPTEPKKLE ENEVIPKRIS PVEESEDVSN KVSMSSTVQG SNIFERTE
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