Recombinant human Annexin A2/ANXA2 protein

Annexin A2 belongs to a family of calcium-dependent membrane and phospholipid binding proteins. It plays a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. Recombinant Annexin A2 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV (PAP-IV), Protein I, p36, ANX2, ANX2L4, CAL1H, LPC2D

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

42.8 kDa (376aa) confirmed by MALDI-TOF

Additionnal Information

Annexin A2, ATGP0467-10 µg, ATGP0467-20 µg, ATGP0467-50 µg, ATGP0467-100 µg, ATGP0467-250 µg, ATGP0467-500 µg, ATGP0467-1 mg, ATGP0467-10, ATGP0467-20, ATGP0467-50, ATGP0467-100, ATGP0467-250, ATGP0467-500, ATGP0467-1

References & Citations

Emans N., et al. (1993) J. Cell Biol. 120 (6) :1357-69; ; Zhao P, ., et al. (2010) Cancer Sci. 101 (2) :387-95.

Other References

Sakamoto N et al., Anti-annexin A4 antibody as a biomarker for desquamative interstitial pneumonia. (J Autoimmun. 2025) {https://pubmed.ncbi.nlm.nih.gov/40156961/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.1M NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001002857.1

Uniprot Accession Number

P07355

Species

Human

AA Sequence

MST VHEILCKLSL EGDHSTPPSA YGSVKAYTNF DAERDALNIE TAIKTKGVDE VTIVNILTNR SNAQRQDIAF AYQRRTKKEL ASALKSALSG HLETVILGLL KTPAQYDASE LKASMKGLGT DEDSLIEIIC SRTNQELQEI NRVYKEMYKT DLEKDIISDT SGDFRKLMVA LAKGRRAEDG SVIDYELIDQ DARDLYDAGV KRKGTDVPKW ISIMTERSVP HLQKVFDRYK SYSPYDMLES IRKEVKGDLE NAFLNLVQCI QNKPLYFADR LYDSMKGKGT RDKVLIRIMV SRSEVDMLKI RSEFKRKYGK SLYYYIQQDT KGDYQKALLY LCGGDD