Recombinant human Annexin A6/ANXA6 protein

Annexin A6 belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Recombinant Annexin A6 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

ANXA6, ANX6, CBP68, 67 kDa calelectrin, Annexin A6, Annexin VI p68, AnnexinA6, AnnexinVI, ANX 6, ANX A6, ANXA 6, Calcium binding protein p68, Calelectrin, Calphobindin II, CalphobindinII, CBP 68, Chromobindin 20, Chromobindin20, CPB II, CPBII, Lipocortin VI, LipocortinVI, p68, P70, Protein III, ProteinIII.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

78.0 kDa (693aa)

Additionnal Information

Annexin A6, ANXA6, ANX6, CBP68, 67 kDa calelectrin, Annexin A6, Annexin VI p68, AnnexinA6, AnnexinVI, ANX 6, ANX A6, ANXA 6, Calcium binding protein p68, Calelectrin, Calphobindin II, CalphobindinII, CBP 68, Chromobindin 20, Chromobindin20, CPB II, CPBII, Lipocortin VI, LipocortinVI, p68, P70, Protein III, ProteinIII., ATGP0459-10 µg, ATGP0459-20 µg, ATGP0459-50 µg, ATGP0459-100 µg, ATGP0459-250 µg, ATGP0459-500 µg, ATGP0459-1 mg, ATGP0459-10, ATGP0459-20, ATGP0459-50, ATGP0459-100, ATGP0459-250, ATGP0459-500, ATGP0459-1

References & Citations

Benz J., et al. (1996) J. Mol. Biol. 260:638-643; ; Takagi H., et al. (2003) J. Cell. Sci. 115:3309-18.

Other References

Sakamoto N et al., Anti-annexin A4 antibody as a biomarker for desquamative interstitial pneumonia. (J Autoimmun. 2025) {https://pubmed.ncbi.nlm.nih.gov/40156961/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001146.2

Uniprot Accession Number

P08133

Species

Human

AA Sequence

MAKPAQGAKY RGSIHDFPGF DPNQDAEALY TAMKGFGSDK EAILDIITSR SNRQRQEVCQ SYKSLYGKDL IADLKYELTG KFERLIVGLM RPPAYCDAKE IKDAISGIGT DEKCLIEILA SRTNEQMHQL VAAYKDAYER DLEADIIGDT SGHFQKMLVV LLQGTREEDD VVSEDLVQQD VQDLYEAGEL KWGTDEAQFI YILGNRSKQH LRLVFDEYLK TTGKPIEASI RGELSGDFEK LMLAVVKCIR STPEYFAERL FKAMKGLGTR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS LYSMIKNDTS GEYKKTLLKL SGGDDDAAGQ FFPEAAQVAY QMWELSAVAR VELKGTVRPA NDFNPDADAK ALRKAMKGLG TDEDTIIDII THRSNVQRQQ IRQTFKSHFG RDLMTDLKSE ISGDLARLIL GLMMPPAHYD AKQLKKAMEG AGTDEKALIE ILATRTNAEI RAINEAYKED YHKSLEDALS SDTSGHFRRI LISLATGHRE EGGENLDQAR EDAQVAAEIL EIADTPSGDK TSLETRFMTI LCTRSYPHLR RVFQEFIKMT NYDVEHTIKK EMSGDVRDAF VAIVQSVKNK PLFFADKLYK SMKGAGTDEK TLTRIMVSRS EIDLLNIRRE FIEKYDKSLH QAIEGDTSGD FLKALLALCG GED