Recombinant human Annexin A3/ANXA3 protein

Annexin A3, also known as ANXA3, belong to the calcium dependent phospholipid binding protein family which play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1, 2 cyclic phosphates to form inositol 1 phosphate. It has been reported for the signaling cascade in rat liver regeneration. Recombinant human ANXA3 was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Annexin-3, Lipocortin III, Placental anticoagulant protein III, 35-alpha calcimedin, ANXA3, ANX3, Annexin A3, Annexin III, PAP III, Inositol 1 2 cyclic phosphate 2 phosphohydrolase

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

36.3 kDa (323aa) confirmed by MALDI-TOF

Additionnal Information

Placental anticoagulant protein III, Placental anticoagulant protein 3, PAP-III, PAPIII, PAP-3, PAP3, PAP III, PAP 3, Lipocortin-III, LipocortinIII, Lipocortin-3, Lipocortin3, Lipocortin III, Lipocortin 3, Inositol 1 2 cyclic phosphate 2 phosphohydrolase, ANXA3, ANX3, ANX A3, ANX A 3, ANX 3, Annexin-III, AnnexinIII, Annexin-3, Annexin3, Annexin III, Annexin A3, Annexin 3, 35-alpha calcimedin, 35alpha calcimedin, 35 alpha calcimedin, ATGP0453-10 µg, ATGP0453-20 µg, ATGP0453-50 µg, ATGP0453-100 µg, ATGP0453-250 µg, ATGP0453-500 µg, ATGP0453-1 mg, ATGP0453-010, ATGP0453-020, ATGP0453-050, ATGP0453-100, ATGP0453-250, ATGP0453-500, ATGP0453-01M

References & Citations

Harashima M., et al. (2008) J Biochem. 143 (4) :537-45.; ; Tait J., et al. (1991) Genomics. 10 (2) :441-8.;

Other References

Sakamoto N et al., Anti-annexin A4 antibody as a biomarker for desquamative interstitial pneumonia. (J Autoimmun. 2025) {https://pubmed.ncbi.nlm.nih.gov/40156961/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_005130

Uniprot Accession Number

P12429

Species

Human

AA Sequence

MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN AQRQLIVKEY QAAYGKELKD DLKGDLSGHF EHLMVALVTP PAVFDAKQLK KSMKGAGTNE DALIEILTTR TSRQMKDISQ AYYTVYKKSL GDDISSETSG DFRKALLTLA DGRRDESLKV DEHLAKQDAQ ILYKAGENRW GTDEDKFTEI LCLRSFPQLK LTFDEYRNIS QKDIVDSIKG ELSGHFEDLL LAIVNCVRNT PAFLAERLHR ALKGIGTDEF TLNRIMVSRS EIDLLDIRTE FKKHYGYSLY SAIKSDTSGD YEITLLKICG GDD