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Recombinant human ATOX1 protein

Copper transport protein ATOX1, also known as HAH1, a metal transport protein that belongs to the ATX1 family. ATOX1 is involved in cellular antioxidant defense and can bind and deliver cytosolic copper to the copper ATPase proteins. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. Recombinant human ATOX1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Copper transport protein ATOX1, Antioxidant protein 1, ATX1, HAH1, Copper transport protein ATOX1 ATX1, Copper transport protein, Metal transport protein.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

9.5 kDa (88aa) confirmed by MALDI-TOF

Additionnal Information

ATOX1, Copper transport protein ATOX1, Antioxidant protein 1, ATX1, HAH1, Copper transport protein ATOX1 ATX1, Copper transport protein, Metal transport protein., ATGP0434-10 µg, ATGP0434-20 µg, ATGP0434-50 µg, ATGP0434-100 µg, ATGP0434-250 µg, ATGP0434-500 µg, ATGP0434-1 mg, ATGP0434-10, ATGP0434-20, ATGP0434-50, ATGP0434-100, ATGP0434-250, ATGP0434-500, ATGP0434-1

References & Citations

Klomp LW., et al. (1997) J Biol Chem. 272 (14) :9221-6. ; ; Hamzal I., et al. (1999) Proc Natl Acad Sci uSA. 96 (23) :13363-8.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Scientific Category

Heat Shock Proteins

NCBI Accession Number

NP_004036

Uniprot Accession Number

O00244

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE

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