Recombinant human MAT2B protein

Methionine adenosyltransferase II, beta (MAT II beta) belongs to the methionine adenosyltransferase (MAT) family. MAT II beta catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Its expression in hepatoma cell lines may lead to increase DNA synthesis and thereby participate to cell proliferation. Recombinant human MAT II beta was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

2410018D16Rik, AI182287, Au022853, Beta 1110064C04Rik, Beta regulatory subunit of methionine adenosyltransferase, dTDP 4 keto 6 deoxy D glucose 4 reductase, MAT II, MAT II beta, MAT2B, Methionine adenosyltransferase 2 beta subunit, Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II, Methionine adenosyltransferase II beta, MGC12237, Nbla02999, OTTMuSP00000005600, Putative protein product of Nbla02999, RP23-382C18.2, SDR23E1, Short chain dehydrogenase/reductase family 23E member 1, TGR

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

36.4 kDa (323aa) confirmed by MALDI-TOF

Additionnal Information

2410018D16Rik, AI182287, Au022853, Beta 1110064C04Rik, Beta regulatory subunit of methionine adenosyltransferase, dTDP 4 keto 6 deoxy D glucose 4 reductase, MAT II, MAT II b, MAT II beta, MAT2B, MATIIbeta, Methionine adenosyltransferase 2 beta subunit, Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II, Methionine adenosyltransferase II beta, MGC12237, Nbla02999, OTTMuSP00000005600, Putative protein product of Nbla02999, RP23-382C18.2, SDR23E1, Short chain dehydrogenase/reductase family 23E member 1, TGR, ATGP0425-10 µg, ATGP0425-20 µg, ATGP0425-50 µg, ATGP0425-100 µg, ATGP0425-250 µg, ATGP0425-500 µg, ATGP0425-1 mg, ATGP0425-010, ATGP0425-020, ATGP0425-050, ATGP0425-100, ATGP0425-250, ATGP0425-500, ATGP0425-01M

References & Citations

Steele W., et al. (2005) Reprod Biomed Online. 10 (6) :755-66.; ; LeGros L., et al. (2001) J Biol Chem. 276 (27) :24918-24.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

AAH05218

Uniprot Accession Number

Q9NZL9

Species

Human

AA Sequence

MPEMPEDMEQ EEVNIPNRRV LVTGATGLLG RAVHKEFQQN NWHAVGCGFR RARPKFEQVN LLDSNAVHHI IHDFQPHVIV HCAAERRPDV VENQPDAASQ LNVDASGNLA KEAAAVGAFL IYISSDYVFD GTNPPYREED IPAPLNLYGK TKLDGEKAVL ENNLGAAVLR IPILYGEVEK LEESAVTVMF DKVQFSNKSA NMDHWQQRFP THVKDVATVC RQLAEKRMLD PSIKGTFHWS GNEQMTKYEM ACAIADAFNL PSSHLRPITD SPVLGAQRPR NTQLDCSKLE TLGIGQRTPF RIGIKESLWP FLIDKRWRQT VFH