What is the catalog number for Recombinant human PNMT protein?

The catalog number for Recombinant human PNMT protein is ATGP0417-100.

What sizes are available for Recombinant human PNMT protein?

Recombinant human PNMT protein is available in the following size(s): 100 µg.

Is Recombinant human PNMT protein in stock?

Recombinant human PNMT protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human PNMT protein

PNMT, also known as phenylethanolamine N-methyltransferase, is an enzyme found in the adrenal medulla that catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline) . The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Recombinant PNMT protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Phenylethanolamine N-methyltransferase, PENT, PNMTase, Noradrenaline-N-methyltransferase, Phenylethanolamine N-methyltransferase

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

30.8 kDa (282aa) confirmed by MALDI-TOF

Additionnal Information

PNMT, Phenylethanolamine N-methyltransferase, PENT, PNMTase, Noradrenaline-N-methyltransferase, Phenylethanolamine N-methyltransferase, ATGP0417-10 µg, ATGP0417-20 µg, ATGP0417-50 µg, ATGP0417-100 µg, ATGP0417-250 µg, ATGP0417-500 µg, ATGP0417-1 mg, ATGP0417-10, ATGP0417-20, ATGP0417-50, ATGP0417-100, ATGP0417-250, ATGP0417-500, ATGP0417-1

References & Citations

Kaneda N., et al. (1998) Biochem Biophys Res Commun. 249 (2) :405-9.; ; Ji Y., et al. (2005) J. Neurochem. 95:1766-1776.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Enzymes & Proteases

NCBI Accession Number

NP_002677

Uniprot Accession Number

P11086

Species

Human

AA Sequence

MSGADRSPNA GAAPDSAPGQ AAVASAYQRF EPRAYLRNNY APPRGDLCNP NGVGPWKLRC LAQTFATGEV SGRTLIDIGS GPTVYQLLSA CSHFEDITMT DFLEVNRQEL GRWLQEEPGA FNWSMYSQHA CLIEGKGECW QDKERQLRAR VKRVLPIDVH QPQPLGAGSP APLPADALVS AFCLEAVSPD LASFQRALDH ITTLLRPGGH LLLIGALEES WYLAGEARLT VVPVSEEEVR EALVRSGYKV RDLRTYIMPA HLQTGVDDVK GVFFAWAQKV GL