Recombinant human Calnexin protein

Calnexin, also known as IP90, p88 and p90, is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, endoplasmic reticulum (ER) -associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Recombinant Calnexin protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CNX, IP90, P90, CANX, FLJ26570, Histocompatibility complex class I antigen binding protein p88

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

52.5 kDa (462aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

Calnexin, CNX, IP90, P90, CANX, FLJ26570, Histocompatibility complex class I antigen binding protein p88, ATGP0388-10 µg, ATGP0388-20 µg, ATGP0388-50 µg, ATGP0388-100 µg, ATGP0388-250 µg, ATGP0388-500 µg, ATGP0388-1 mg, ATGP0388-10, ATGP0388-20, ATGP0388-50, ATGP0388-100, ATGP0388-250, ATGP0388-500, ATGP0388-1

References & Citations

Wang B., et al. (2009) Immunology. 128 (1) :43-57. ; ; Millar DJ., et al. (2009) Proteomics. 9 (9) :2355-72.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT and 20% glycerol

Scientific Category

Heat Shock Proteins

NCBI Accession Number

NP_001019820.1

Uniprot Accession Number

P27824

Species

Human

AA Sequence

MHDGHDDDVI DIEDDLDDVI EEVEDSKPDT TAPPSSPKVT YKAPVPTGEV YFADSFDRGT LSGWILSKAK KDDTDDEIAK YDGKWEVEEM KESKLPGDKG LVLMSRAKHH AISAKLNKPF LFDTKPLIVQ YEVNFQNGIE CGGAYVKLLS KTPELNLDQF HDKTPYTIMF GPDKCGEDYK LHFIFRHKNP KTGIYEEKHA KRPDADLKTY FTDKKTHLYT LILNPDNSFE ILVDQSVVNS GNLLNDMTPP VNPSREIEDP EDRKPEDWDE RPKIPDPEAV KPDDWDEDAP AKIPDEEATK PEGWLDDEPE YVPDPDAEKP EDWDEDMDGE WEAPQIANPR CESAPGCGVW QRPVIDNPNY KGKWKPPMID NPSYQGIWKP RKIPNPDFFE DLEPFRMTPF SAIGLELWSM TSDIFFDNFI ICADRRIVDD WANDGWGLKK AADGAAEPGV VGQMIEAAEE RP