Recombinant human NDRG1 protein

N-myc downstream regulated gene (NDRG) -1 is one of 4 members of the NDRG alpha/beta-hydrolase family. This protein is classified in databases as a tumor suppressor and heavy metal-response protein. Its functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. Mutation in the NDRG1 gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom (HMSNL), a severe autosomal recessive form of Charcot-Marie-Tooth (CMT) disease. Recombinant human NDRG1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

N-myc downstream regulated 1, CAP43, CMT4D, DRG1, GC4, HMSNL, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5, N-myc downstream regulated 1 TDD5, 42 kDa, anti-GC4, cmt4d, Differentiation related gene1 protein, Drg 1, hmsnl, Human mRNA for RTP complete cds, NDRG1, tdds, N myc downstream regulated gene 1, N myc downstream regulated gene 1 protein, Ndr 1, ndr1, NDRG 1, NDRG1 protein, Protein nickel specific induction protein, Nickel specific induction protein Cap43, nmsl, Nmyc downstream regulated, reduced in tumor, reducin, Nmyc downstream regulated gene1, Nmyc downstream regulated gene1 protein, Protein regulated by oxygen 1, Protein regulated by oxygen1, proxy1, Reducing agents and tunicamycin responsive protein, tunicamycin-responsive protein

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

43.9 kDa (402aa) confirmed by MALDI-TOF

Additionnal Information

NDRG1, ATGP0386-10 µg, ATGP0386-20 µg, ATGP0386-50 µg, ATGP0386-100 µg, ATGP0386-250 µg, ATGP0386-500 µg, ATGP0386-1 mg, ATGP0386-10, ATGP0386-20, ATGP0386-50, ATGP0386-100, ATGP0386-250, ATGP0386-500, ATGP0386-1