Recombinant human CX3CL1/Fractalkine protein

CX3CL1, also known as fractalkine. CX3CL1 has a unique CX3C cysteine motif near the amino terminus and is the first member of a fourth branch of the chemokine superfamily. unlike other known chemokines, CX3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucin like stalk. It is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Also, CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Recombinant human CX3CL1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Chemokine (C-X3-C motif) ligand 1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, CX3CL1, Chemokine (C-X3-C motif) ligand 1, small inducible cytokine subfamily D (Cys-X3-Cys) member 1 (fractalkine, neurotactin), fractalkine, neurotactin

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

10.9 kDa (97aa) confirmed by MALDI-TOF

Additionnal Information

CX3CL1, Fractalkine, Chemokine (C-X3-C motif) ligand 1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, CX3CL1, Chemokine (C-X3-C motif) ligand 1, small inducible cytokine subfamily D (Cys-X3-Cys) member 1 (fractalkine, neurotactin), fractalkine, neurotactin, ATGP0380-10 µg, ATGP0380-20 µg, ATGP0380-50 µg, ATGP0380-100 µg, ATGP0380-250 µg, ATGP0380-500 µg, ATGP0380-1 mg, ATGP0380-10, ATGP0380-20, ATGP0380-50, ATGP0380-100, ATGP0380-250, ATGP0380-500, ATGP0380-1