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Recombinant human CCL5/RANTES protein

Rantes, also known as CCL5, is the protein classified as a chemotactic cytokine or chemokine. This protein is a chemotactic for blood monocytes, memory T helper cells, eosinophils and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. Rantes also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. It is also an HIV-suppressive factor released from CD8+ T cells. Recombinant RANTES protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

TCP228, T cell specific RANTES protein, T cell specific protein p288, Small inducible cytokine subfamily A (Cys Cys) member 5, Small inducible cytokine A5 Beta chemokine RANTES precursor, Small inducible cytokine A5 (RANTES), Small inducible cytokine A5, SISd, SIS delta, SCYA5, Regulated upon activation normally T expressed and presumably secreted, MGC17164, Eosinophil chemotactic cytokine, EoCP, D17S136E, Chemokine CC Motif Ligand 5, CCL5

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

7.9 kDa (69aa) confirmed by MALDI-TOF

Additionnal Information

TCP228, TCP 228, T cell specific RANTES protein, T cell specific protein p288, Small inducible cytokine subfamily A (Cys Cys) member 5, Small inducible cytokine A5 Beta chemokine RANTES precursor, Small inducible cytokine A5 (RANTES), Small inducible cytokine A5, SISd, SIS delta, SCYA5, SCYA 5, Regulated upon activation normally T expressed and presumably secreted, MGC17164, Eosinophil chemotactic cytokine, EoCP, D17S136E, Chemokine CC Motif Ligand 5, Chemokine (C C motif) ligand 5, CCL5, CCL 5, ATGP0374-10 µg, ATGP0374-20 µg, ATGP0374-50 µg, ATGP0374-100 µg, ATGP0374-250 µg, ATGP0374-500 µg, ATGP0374-1 mg, ATGP0374-010, ATGP0374-020, ATGP0374-050, ATGP0374-100, ATGP0374-250, ATGP0374-500, ATGP0374-01M

References & Citations

Maghazachi Aa., et al. (1996) Eur J Immunol. 26 (2) :315-9. ; ; Duggal P., et al. (2005) J Acguir Immune Defic Syndr. 38 (5) :584-9.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_002976

Uniprot Accession Number

P13501

Species

Human

AA Sequence

MSPYSSDTTP CCFAYIARPL PRAHIKEYFY TSGKCSNPAV VFVTRKNRQV CANPEKKWVR EYINSLEMS

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