Recombinant human AHSP protein

AHSP (Alpha-hemoglobin stabilizing protein), also known as ERAF (Erythroid associated factor), is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of alpha-hemoglobin during normal erythroid cell development. It specifically protects free alpha-hemoglobin from precipitation in live cells and in solution. This protein is downregulated in transmissible spongiform encephalopathies (TSEs) . It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia. Recombinant AHSP protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Alpha-hemoglobin stabilizing protein, ERAF, EDRF, Alpha-hemoglobin stabilizing protein Alpha hemoglobin stabilizing protein, Erythroid associated factor, Erythroid differentiation associated factor, Erythroid differentiation related factor

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

11.8 kDa (102aa) confirmed by MALDI-TOF

Additionnal Information

AHSP, Alpha-hemoglobin stabilizing protein, ERAF, EDRF, Alpha-hemoglobin stabilizing protein Alpha hemoglobin stabilizing protein, Erythroid associated factor, Erythroid differentiation associated factor, Erythroid differentiation related factor, ATGP0369-10 µg, ATGP0369-20 µg, ATGP0369-50 µg, ATGP0369-100 µg, ATGP0369-250 µg, ATGP0369-500 µg, ATGP0369-1 mg, ATGP0369-10, ATGP0369-20, ATGP0369-50, ATGP0369-100, ATGP0369-250, ATGP0369-500, ATGP0369-1