Recombinant human BMP-5 (monomer) protein
BMP5 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. BMP5 may play a role in certain cancers. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. Recombinant BMP5 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Product Specifications
Product Name Alternative
Bone morphogenetic protein 5, BMP-5, MGC34244
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
15.7 kDa (139aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Mailhot G., et al. (2008) . J Cell Physiol. 214 (1) :56-64. ; ; Matus DQ., et al. (2006) . Proc Natl Acad Sci u S A. 103 (30) :11195-200.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_066551
Uniprot Accession Number
P22003
Species
Human
AA Sequence
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