Recombinant human BMP-5 (monomer) protein

BMP5 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. BMP5 may play a role in certain cancers. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. Recombinant BMP5 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Product Specifications

Product Name Alternative

Bone morphogenetic protein 5, BMP-5, MGC34244

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

15.7 kDa (139aa) confirmed by MALDI-TOF

Additionnal Information

MGC34244, Bone morphogenetic protein5, Bone morphogenetic protein 5, BMP5 monomer, BMP-5, BMP5, BMP 5, ATGP0350-10 µg, ATGP0350-20 µg, ATGP0350-50 µg, ATGP0350-100 µg, ATGP0350-250 µg, ATGP0350-500 µg, ATGP0350-1 mg, ATGP0350-010, ATGP0350-020, ATGP0350-050, ATGP0350-100, ATGP0350-250, ATGP0350-500, ATGP0350-01M

References & Citations

Mailhot G., et al. (2008) . J Cell Physiol. 214 (1) :56-64. ; ; Matus DQ., et al. (2006) . Proc Natl Acad Sci u S A. 103 (30) :11195-200.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_066551

Uniprot Accession Number

P22003

Species

Human

AA Sequence

MAANKRKNQN RNKSSSHQDS SRMSSVGDYN TSEQKQACKK HELYVSFRDL GWQDWIIAPE GYAAFYCDGE CSFPLNAHMN ATNHAIVQTL VHLMFPDHVP KPCCAPTKLN AISVLYFDDS SNVILKKYRN MVVRSCGCH