Recombinant human Serpin B5/Maspin protein
Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas. Recombinant human Maspin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
44.2 kDa (395aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Lockett J., et al. (2006) . J Cell Biochem. 97 (4) :651-60.; ; Khalkhali Ellis Z., et al. (2006) . Clin Cancer Res. 12 (24) :7279-83.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Tags & Cell Markers
NCBI Accession Number
AY893387
Uniprot Accession Number
P36952
Species
Human
AA Sequence
Frequently Asked Questions
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