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Recombinant human S100A4 protein

S100A4, also known as S100 calcium-binding protein A4, belongs to the S100 super-family of proteins containing 2 EF-hand calcium binding domains. This protein is ubiquitously overexpressed and is localized in the cytoplasm and/or nucleus. S100A4 may play a role in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of the S100A4 gene have been implicated in tumor metastasis. Recombinant human S100A4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

S100 calcium-binding protein A4, S100 calcium-binding protein A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, Metastasin, S100A4, S100 calcium-binding protein A4 Protein S100 A4, S100 calcium binding protein A4.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

13.8 kDa (121aa) confirmed by MALDI-TOF

Additionnal Information

S100A4, S100 calcium-binding protein A4, S100 calcium-binding protein A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, Metastasin, S100A4, S100 calcium-binding protein A4 Protein S100 A4, S100 calcium binding protein A4., ATGP0319-10 µg, ATGP0319-20 µg, ATGP0319-50 µg, ATGP0319-100 µg, ATGP0319-250 µg, ATGP0319-500 µg, ATGP0319-1 mg, ATGP0319-10, ATGP0319-20, ATGP0319-50, ATGP0319-100, ATGP0319-250, ATGP0319-500, ATGP0319-1

References & Citations

Sherbet GV., et al. (2009) Cancer Lett. 280 (1) :15-30.; ; Ambartsumian N., et al. (1995) Gene. 159 (1) :125-30.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_002952.1

Uniprot Accession Number

P26447

Species

Human

AA Sequence

MACPLEKALD VMVSTFHKYS GKEGDKFKLN KSELKELLTR ELPSFLGKRT DEAAFQKLMS NLDSNRDNEV DFQEYCVFLS CIAMMCNEFF EGFPDKQPRK K

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