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Recombinant human XCL1/Lymphotactin protein

Lymphotactin, also known as XCL1, is member of gamma or C subfamily of chemokines. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. The expression of lymphotactin is restricted to activated T cells such as activated CD8+ T cells and other calss IMHC restricted T cells. Since lymphotactin is produced by lymphocytes and acts on lymphocytes, it is speculated that it is a messenger in T cell chemoattraction. Recombinant human XCL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Chemokine (C motif) ligand 1, XCL1, ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1, Chemokine (C motif) ligand 1, Lymphotactin/XCL1, Chemokine (C motif) ligand 1 C motif chemokine 1, SCM 1 alpha, SCM1, SCYC1, Chemokine C Motif Ligand 1, Small inducible cytokine C1, Small Inducible Cytokine Subfamily C Member 1, XC chemokine ligand 1, XCL1.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

12.5 kDa (114aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

XCL1, Lymphotactin, Chemokine (C motif) ligand 1, XCL1, ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1, Chemokine (C motif) ligand 1, Lymphotactin/XCL1, Chemokine (C motif) ligand 1 C motif chemokine 1, SCM 1 alpha, SCM1, SCYC1, Chemokine C Motif Ligand 1, Small inducible cytokine C1, Small Inducible Cytokine Subfamily C Member 1, XC chemokine ligand 1, XCL1., ATGP0316-10 µg, ATGP0316-20 µg, ATGP0316-50 µg, ATGP0316-100 µg, ATGP0316-250 µg, ATGP0316-500 µg, ATGP0316-1 mg, ATGP0316-10, ATGP0316-20, ATGP0316-50, ATGP0316-100, ATGP0316-250, ATGP0316-500, ATGP0316-1

References & Citations

Yoshida T., et al. (1996) . FEBS Lett. 395 (1) :82-8.; ; Kennedy J., et al. (1995) . J Immunol. 155 (1) :203-9.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol 2mM DTT, 0.2 M NaCl.

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_002986

Uniprot Accession Number

P47992

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG

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