Recombinant human Pentraxin 3/PTX3 protein

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. Pentraxin 3 is produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Recombinant human Pentraxin 3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

TNFAIP5, TSG-14, Pentraxin 3, AI607804, Pentaxin 3, Pentaxin-related protein PTX3, Pentraxin-related gene, rapidly induced by IL-1 beta, Pentraxin-related gene, PTX3, TSG14, Tumor necrosis factor-inducible gene 14 protein, Tumor necrosis factor-inducible protein TSG-14

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

44.4 kDa (401aa) confirmed by MALDI-TOF

Additionnal Information

Pentraxin3, TSG1, ATGP0312-10 µg, ATGP0312-20 µg, ATGP0312-50 µg, ATGP0312-100 µg, ATGP0312-250 µg, ATGP0312-500 µg, ATGP0312-1 mg, ATGP0312-10, ATGP0312-20, ATGP0312-50, ATGP0312-100, ATGP0312-250, ATGP0312-500, ATGP0312-1

References & Citations

Imamura M., et al. (2007) . Cell Immunol. 248 (2) :86-94.; ; Allens VV., et al. (1994) . Blood. 84 (10) :3483-93.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_002843.1

Uniprot Accession Number

P26022

Species

Human

AA Sequence

ENS DDYDLMYVNL DNEIDNGLHP TEDPTPCDCG QEHSEWDKLF IMLENSQMRE RMLLQATDDV LRGELQRLRE ELGRLAESLA RPCAPGAPAE ARLTSALDEL LQATRDAGRR LARMEGAEAQ RPEEAGRALA AVLEELRQTR ADLHAVQGWA ARSWLPAGCE TAILFPMRSK KIFGSVHPVR PMRLESFSAC IWVKATDVLN KTILFSYGTK RNPYEIQLYL SYQSIVFVVG GEENKLVAEA MVSLGRWTHL CGTWNSEEGL TSLWVNGELA ATTVEMATGH IVPEGGILQI GQEKNGCCVG GGFDETLAFS GRLTGFNIWD SVLSNEEIRE TGGAESCHIR GNIVGWGVTE IQPHGGAQYV S