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Recombinant human Chromogranin A/CHGA (19-131aa) protein

Vasostatin 2 is the N-terminal fragment (19-131 aa) derived from the cleavage of chromogranin A (CgA) which is a member of the chromogranin/secretogranin (granins) family of neuroendocrine secretory proteins. Vasostatin 2 has been shown to exert several biological activities on several tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion. Recombinant human Vasostatin 2 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Cga, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin-2, EA-92, ES-43, Pancreastatin, parastatin, PHE5, PHES, SS-18, WA-8, WE-14, LF-19, Catestatin 2, SL21, AL-11, GV-19, GR-44, ER-37, GE-25, Serpinin-RRG, Serpinin, p-Glu serpinin precursor

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

12.8 kDa (114aa) confirmed by MALDI-TOF

Additionnal Information

Vasostatin2, Vasostatin 2, Vasostatin, SP-I, SPI, SP-1, SP1, SP I, SP 1, Pituitary secretory protein I, Parathyroid secretory protein 1, Parastatin, Pancreastatin, Chromogranin-A isoform 1, Chromogranin-A, ChromograninA, Chromogranin A precursor, Chromogranin A parathyroid secretory protein 1, Chromogranin A isoform 1, Chromogranin A, CHGA, CHG A, CGA, beta Granin, Chromogranin-A precursor, Chromogranin-A parathyroid secretory protein 1, ATGP0309-10 µg, ATGP0309-20 µg, ATGP0309-50 µg, ATGP0309-100 µg, ATGP0309-250 µg, ATGP0309-500 µg, ATGP0309-1 mg, ATGP0309-010, ATGP0309-020, ATGP0309-050, ATGP0309-100, ATGP0309-250, ATGP0309-500, ATGP0309-01M

References & Citations

Tota BW., et al. (2008) . Curr Med Chem. 15 (14) :1444-51; ; Blois A., et al. (2006) . Requl pept. 134 (1) :30-7;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_001266

Uniprot Accession Number

P10645

Species

Human

AA Sequence

MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVME

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