Recombinant human SUMO1 protein

SuMO-1, also known as small ubiquitin-related modifier 1, is a member of the SuMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SuMO-1 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. Recombinant human SuMO1 protein was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

SMT3 suppressor of mif two 3 homolog 1 isoform a, SMT3 suppressor of mif two 3 homolog 1 isoform a, DAP-1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, uBL1, SMT3 suppressor of mif two 3 homolog 1 isoform a GAP modifying protein 1, GMP 1, PIC 1, Sentrin, Sentrin 1, Small ubiquitin related modifier 1, SMT3 homolog 3, uBL 1, SMT3 suppressor of mif two 3 homolog 1, Sumo1, ubiquitin homology domain protein PIC1, ubiquitin Like 1, ubiquitin like protein SMT3C, ubiquitin like protein uBL1.

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

11.1 kDa (97aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

SUMO1, SMT3 suppressor of mif two 3 homolog 1 isoform a, SMT3 suppressor of mif two 3 homolog 1 isoform a, DAP-1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, uBL1, SMT3 suppressor of mif two 3 homolog 1 isoform a GAP modifying protein 1, GMP 1, PIC 1, Sentrin, Sentrin 1, Small ubiquitin related modifier 1, SMT3 homolog 3, uBL 1, SMT3 suppressor of mif two 3 homolog 1, Sumo1, ubiquitin homology domain protein PIC1, ubiquitin Like 1, ubiquitin like protein SMT3C, ubiquitin like protein uBL1., ATGP0301-10 µg, ATGP0301-20 µg, ATGP0301-50 µg, ATGP0301-100 µg, ATGP0301-250 µg, ATGP0301-500 µg, ATGP0301-1 mg, ATGP0301-10, ATGP0301-20, ATGP0301-50, ATGP0301-100, ATGP0301-250, ATGP0301-500, ATGP0301-1

References & Citations

Evdokimov E., et al. (2008), J Cell Sci, 121:4106-13.; ; Hecker CM., et al. (2006) . J Biol Chem. 281 (23) :16117-27.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Ubiquitination

NCBI Accession Number

NP_003343

Uniprot Accession Number

P63165

Species

Human

AA Sequence

MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGG

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