Recombinant human GRO beta/CXCL2 protein

CXCL2 is a small cytokine belonging to the CXC chemokine family that is also known as Chemokine (C-X-C motif) ligand 2, and macrophage inflammatory protein 2-alpha (MIP2-alpha) . CXCL2 is secreted by activated monocytes, neutrophils and macrophages and expressed at sites of inflammation. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells and suppresses hematopoietic progenitor cell proliferation. Recombinant human CXCL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

C-X-C motif chemokine ligand 2, C-X-C motif chemokine 2, Growth-regulated protein beta, Gro-beta, GRO2, GROB, MIP2A, SCYB2, GRO2 oncogene, Macrophage inflammatory protein 2-alpha, MIP2-alpha , MGSA-b, CINC-2a

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

10.1 kDa (94aa) confirmed by MALDI-TOF

Additionnal Information

CXCL1, GRO Pan, C-X-C motif chemokines 2, C-X-C motif chemokines 2, MIP2-alpha, Gro-beta, CINC-2a, GRO2, GROb, MIP2, MIP2A, SCYB2, C-X-C motif chemokines 2 Chemokine (C X C motif) ligand 2, CINC 2a, CINC2a, CINC3, Chemokine, CXC motif, ligand 2, CXC chemokine, CXCL 2, CXCL2, Cytokine-induced neutrophil chemoattractant 3, GRO 2, GRO b, GRO protein, beta, GRO2 oncogene, GRObeta, Growth regulated protein beta, GROX, Macrophage inflammatory protein 2, Macrophage inflammatory protein 2 alpha, Melanoma growth stimulatory activity beta, MGSA b, MGSA beta, MGSAbeta, MIP 2, MIP 2a, MIP2, MIP2 alpha, MIP2alpha, Scyb, SCYB 2, Small inducible cytokine subfamily B, member 2., ATGP0299-10 µg, ATGP0299-20 µg, ATGP0299-50 µg, ATGP0299-100 µg, ATGP0299-250 µg, ATGP0299-500 µg, ATGP0299-1 mg, ATGP0299-10, ATGP0299-20, ATGP0299-50, ATGP0299-100, ATGP0299-250, ATGP0299-500, ATGP0299-1

References & Citations

Wolpe SD., et al. (1989) . Proc Natl Acad Sci u S A. 86 (2) :612-6.; ; Jerva LF., et al. (1997) . Protein Sci. 6 (8) :1643-52.; ; Pelus LM., et al. (2006) . Exp Hematol. 34 (8) :1010-20.;