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Recombinant human FABP3/H-FABP protein

FABP3 (Fatty acid binding protein 3) is also known as heart fatty acid binding protein and is a member of Fatty acid binding proteins (FABPs) which are a family of small, highly conserved, cytoplasmic proteins to bind long-chain fatty acids and other hydrophobic ligands. FABP3 is abundant in the myocardium and rapidly released from cardiomyocytes into the circulation after the onset of cell damage. Therefore, this protein has been proposed as an early biochemical marker of acute myocardial infarction and a sensitive marker for the detection and evaluation of myocardial damage in patients with heart failure. Recombinant FABP3 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Fatty acid binding protein 3 muscle and heart, H-FABP, M-FABP, MDGI, FABP11, cardiac fabp, Fatty acid binding protein 3, Muscle fatty acid binding protein, 422 protein, Cardiac Fatty Acid Binding Protein, FABP3, Fatty acid binding protein 3 muscle, Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor, Fatty acid binding protein 11, Fatty acid binding protein heart, H FABP, Heart type fatty acid binding protein, M FABP, Mammary derived growth inhibitor, Mylein protein P2 homolog, O FABP, P2 adopocyte protein

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

19.1 kDa (170aa) confirmed by MALDI-TOF

Additionnal Information

FABP3, H-FABP, Fatty acid binding protein 3 muscle and heart, Fatty acid binding protein 3 muscle and heart, H-FABP, M-FABP, MDGI, FABP11, cardiac fabp, Fatty acid binding protein 3, muscle and heart Muscle fatty acid binding protein, 422 protein, Cardiac Fatty Acid Binding Protein, FABP 3.FABP3, Fatty acid binding protein 3 muscle, Fatty acid binding protein 3 muscle and heart, Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor, Fatty acid binding protein 11, Fatty acid binding protein heart, H FABP, Heart type fatty acid binding protein, M FABP, Mammary derived growth inhibitor, Mylein protein P2 homolog, O FABP, P2 adopocyte protein., ATGP0294-10 µg, ATGP0294-20 µg, ATGP0294-50 µg, ATGP0294-100 µg, ATGP0294-250 µg, ATGP0294-500 µg, ATGP0294-1 mg, ATGP0294-10, ATGP0294-20, ATGP0294-50, ATGP0294-100, ATGP0294-250, ATGP0294-500, ATGP0294-1

References & Citations

Troxler RF., et al. (2007) . Hum Genet. 92 (6) :563-6; ; Zanotti G., et al. (1992) . J Biol Chem. 267 (26) :18541-50;

Other References

Crapnell RD, et al. Thermal Detection of Cardiac Biomarkers Heart-Fatty Acid Binding Protein and ST2 Using a Molecularly Imprinted Nanoparticle-Based Multiplex Sensor Platform. (ACS Sens. 2019) {https://pubmed.ncbi.nlm.nih.gov/31571480/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Transportation

NCBI Accession Number

NP_004093

Uniprot Accession Number

P05413

Species

Human

AA Sequence

MVD AFLGTWKLVD SKNFDDYMKS LGVGFATRQV ASMTKPTTII EKNGDILTLK THSTFKNTEI SFKLGVEFDE TTADDRKVKS IVTLDGGKLV HLQKWDGQET TLVRELIDGK LILTLTHGTA VCTRTYEKEA

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