Recombinant human FABP3/H-FABP protein
FABP3 (Fatty acid binding protein 3) is also known as heart fatty acid binding protein and is a member of Fatty acid binding proteins (FABPs) which are a family of small, highly conserved, cytoplasmic proteins to bind long-chain fatty acids and other hydrophobic ligands. FABP3 is abundant in the myocardium and rapidly released from cardiomyocytes into the circulation after the onset of cell damage. Therefore, this protein has been proposed as an early biochemical marker of acute myocardial infarction and a sensitive marker for the detection and evaluation of myocardial damage in patients with heart failure. Recombinant FABP3 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
19.1 kDa (170aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Troxler RF., et al. (2007) . Hum Genet. 92 (6) :563-6; ; Zanotti G., et al. (1992) . J Biol Chem. 267 (26) :18541-50;
Other References
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Transportation
NCBI Accession Number
NP_004093
Uniprot Accession Number
P05413
Species
Human
AA Sequence
MVD AFLGTWKLVD SKNFDDYMKS LGVGFATRQV ASMTKPTTII EKNGDILTLK THSTFKNTEI SFKLGVEFDE TTADDRKVKS IVTLDGGKLV HLQKWDGQET TLVRELIDGK LILTLTHGTA VCTRTYEKEA
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