Recombinant human SUMO2 protein
Small ubiquitin-related modifier 2 (SuMO-2) is a member of the SuMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SuMO-2 protein is involved in diverse cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. This protein is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Recombinant human SuMO2 protein was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
10.6 kDa (93aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Huang WC., et al. (2004) . Eur J Biochem. 271 (20) :4114-22.; ; Tatham MH., et al. (2001) . J Biol Chem. 276 (38) :35368-74.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0)
Scientific Category
Ubiquitination
NCBI Accession Number
NP_008868
Uniprot Accession Number
P61956
Species
Human
AA Sequence
MADEKPKEGV KTENNDHINL KVAGQDGSVV QFKIKRHTPL SKLMKAYCER QGLSMRQIRF RFDGQPINET DTPAQLEMED EDTIDVFQQQ TGG
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