YOD1 cDNA
YOD1 is a highly conserved deubiquitinating enzyme of the ovarian tumor (otubain) family, whose function has yet to be assigned in mammalian cells. YOD1 is a constituent of a multiprotein complex with p97 as its nucleus, suggesting a functional link to a pathway responsible for the dislocation of misfolded proteins from the endoplasmic reticulum. Expression of a YOD1 variant deprived of its deubiquitinating activity imposes a halt on the dislocation reaction, as judged by the stabilization of various dislocation substrates.
Product Specifications
Product Name Alternative
DUBA8, OTUD2, PRO0907
Chromosomal Location
1q32.2
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
Additionnal Information
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Signal Transduction
Omim
612023
NCBI Accession Number
NP_061036.3
Species
Human
Preparation
RNA Reference
NM_018566.3
DNA Size
1047bp
Vector Description
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