HES2 cDNA
HES2 is a member of the HES family and contains one basic helix-loop-helix (bHLH) domain and one orange domain. The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. Activation of Notch signaling pathway leads to activation of HES family genes through the interaction between Notch intracellular domain and RBPSuH (CSL) . HES2 is expressed in a variety of adult and embryonic tissue.
Product Specifications
Product Name Alternative
BHLHb40
Chromosomal Location
1p36.31
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
Additionnal Information
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Epigenomics (Transcription & Translation)
Omim
609970
NCBI Accession Number
NP_061962.2
Species
Human
Preparation
RNA Reference
NM_019089.4
DNA Size
522bp
Vector Description
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