LAMTOR2 cDNA

The product of ROBLD3 is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

Product Name Alternative

ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3

Chromosomal Location

1q22

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGCTGCGCCCCAAGGCTTTGACCCAGGTGCTAAGCCAAGCCAACACTGGAGGCGTCCAGAGCACCCTGCTGCTGAATAACGAGGGATCACTGCTGGCCTACTCTGGTTACGGGGACACTGACGCCCGGGTCACCGCTGCCATAGCCAGTAACATCTGGGCCGCCTACGACCGGAACGGGAACCAAGCGTTTAATGAAGACAATCTCAAATTCATCCTCATGGACTGCATGGAGGGCCGTGTAGCCATCACCCGAGTGGCCAACCTTCTGCTGTGTATGTATGCCAAGGAGACCGTGGGCTTTGGAATGCTCAAGGCCAAGGCCCAGGCTTTGGTGCAGTACCTGGAGGAGCCCCTCACCCAAGTGGCGGCATCTTAA

Additionnal Information

LAMTOR2, ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3, LAMTOR2, ATGD0210-10 µg, ATGD0210-20 µg, ATGD0210-50 µg, ATGD0210-100 µg, ATGD0210-250 µg, ATGD0210-500 µg, ATGD0210-1 mg, ATGD0210-10, ATGD0210-20, ATGD0210-50, ATGD0210-100, ATGD0210-250, ATGD0210-500, ATGD0210-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Signal Transduction

Omim

610389

NCBI Accession Number

NP_054736.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_014017.3

DNA Size

378bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.