SNRPE cDNA

Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3-end processing. May indirectly play a role in hair development.

Product Specifications

Product Name Alternative

B-raf, HYPT11, Sm-E, SME

Chromosomal Location

1q32

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCGTACCGTGGCCAGGGTCAGAAAGTGCAGAAGGTTATGGTGCAGCCCATCAACCTCATCTTCAGATACTTACAAAATAGATCGCGGATTCAGGTGTGGCTCTATGAGCAAGTGAATATGCGGATAGAAGGCTGTATCATTGGTTTTGATGAGTATATGAACCTTGTATTAGATGATGCAGAAGAGATTCATTCTAAAACAAAGTCAAGAAAACAACTGGGTCGGATCATGCTAAAAGGAGATAATATTACTCTGCTACAAAGTGTCTCCAACTAG

Additionnal Information

SNRPE, B-raf, HYPT11, Sm-E, SME, SNRPE, ATGD0197-10 µg, ATGD0197-20 µg, ATGD0197-50 µg, ATGD0197-100 µg, ATGD0197-250 µg, ATGD0197-500 µg, ATGD0197-1 mg, ATGD0197-10, ATGD0197-20, ATGD0197-50, ATGD0197-100, ATGD0197-250, ATGD0197-500, ATGD0197-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Other

Omim

128260

NCBI Accession Number

NP_003085.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_003094.3

DNA Size

279bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.