LPXN cDNA
The product encoded by LPXN is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Product Specifications
Product Name Alternative
LDPL
Chromosomal Location
11q12.1
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
Additionnal Information
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Cancer
Omim
605390
NCBI Accession Number
NP_001137467.1
Species
Human
Preparation
RNA Reference
NM_001143995.2
DNA Size
1176bp
Vector Description
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