DOK4 cDNA
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity) . Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Product Specifications
Product Name Alternative
IRS-5, IRS5
Chromosomal Location
16q21
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGGCGACCAATTTCAGTGACATCGTCAAGCAAGGCTACGTGAAGATGAAGAGCAGGAAGCTCGGGATCTACCGGAGGTGCTGGCTGGTGTTCCGGAAATCCTCCAGCAAGGGGCCCCAGCGGCTGGAGAAGTATCCAGATGAGAAGTCGGTGTGCCTCCGGGGCTGCCCCAAGGTGACTGAGATCAGCAACGTCAAGTGTGTTACGCGGCTCCCCAAGGAGACCAAGCGGCAGGCGGTGGCCATCATATTCACTGATGACTCGGCACGTACCTTCACCTGCGACTCAGAGCTAGAGGCAGAGGAGTGGTACAAGACACTATCTGTGGAGTGTCTGGGGTCCCGCCTCAACGACATCAGTCTGGGAGAACCTGACCTCCTGGCCCCAGGGGTGCAGTGTGAACAGACAGATCGCTTCAATGTCTTCCTGCTGCCCTGCCCCAACCTGGACGTGTATGGCGAGTGCAAGCTGCAGATCACCCACGAGAACATCTACCTCTGGGACATCCACAACCCCCGTGTGAAGCTCGTCTCGTGGCCCCTCTGCTCACTGCGCCGCTATGGCCGGGATGCCACACGCTTTACCTTCGAGGCTGGCCGGATGTGTGATGCTGGGGAAGGACTCTATACCTTCCAGACACAAGAGGGGGAGCAGATTTACCAGCGCGTCCACAGTGCCACCCTGGCCATCGCAGAGCAGCACAAGCGGGTCCTGCTGGAAATGGAGAAGAACGTGAGGCTGCTGAACAAGGGCACGGAACATTACTCGTATCCCTGCACACCCACGACCATGCTGCCGCGCAGTGCCTACTGGCACCACATCACTGGTTCCCAGAACATCGCCGAAGCCTCCAGCTATGCTGGTGAGGGGTATGGGGCAGCCCAGGCCAGCTCGGAAACAGACCTCCTCAACAGATTCATCCTGCTAAAGCCAAAGCCCAGCCAGGGGGACAGCAGTGAGGCCAAGACCCCATCCCAGTGA
Additionnal Information
DOK4, IRS-5, IRS5, DOK4, ATGD0155-10 µg, ATGD0155-20 µg, ATGD0155-50 µg, ATGD0155-100 µg, ATGD0155-250 µg, ATGD0155-500 µg, ATGD0155-1 mg, ATGD0155-10, ATGD0155-20, ATGD0155-50, ATGD0155-100, ATGD0155-250, ATGD0155-500, ATGD0155-1
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Signal Transduction
Omim
608333
NCBI Accession Number
NP_060580.2
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_018110.3
DNA Size
981bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Curated Selection
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