NXT1 cDNA

NXT1 encoded by this gene is located in the nuclear envelope. NXT1 has protein similarity to nuclear transport factor 2. NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) - and CRM1 (required for chromosome region maintenance) -dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for NXT1.

Product Specifications

Product Name Alternative

MTR2, P15

Chromosomal Location

20p12-p11.2

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCATCTGTGGATTTCAAGACCTATGTGGATCAGGCCTGCAGAGCTGCTGAGGAGTTTGTCAATGTCTACTACACCACCATGGATAAGCGGCGGCGTTTGCTGTCCCGCCTGTACATGGGCACAGCCACCCTGGTCTGGAATGGCAATGCTGTTTCAGGACAAGAATCCTTGAGTGAGTTTTTTGAAATGTTGCCTTCCAGCGAGTTCCAAATCAGCGTGGTAGACTGCCAGCCTGTTCATGATGAAGCCACACCAAGCCAGACCACGGTCCTTGTTGTCATCTGTGGATCAGTGAAGTTTGAGGGGAACAAACAACGGGACTTCAACCAGAACTTCATCCTGACCGCCCAGGCCTCACCCAGCAACACAGTGTGGAAGATCGCAAGTGACTGCTTCCGCTTCCAGGACTGGGCCAGCTAG

Additionnal Information

NXT1, MTR2, P15, NXT1, ATGD0151-10 µg, ATGD0151-20 µg, ATGD0151-50 µg, ATGD0151-100 µg, ATGD0151-250 µg, ATGD0151-500 µg, ATGD0151-1 mg, ATGD0151-10, ATGD0151-20, ATGD0151-50, ATGD0151-100, ATGD0151-250, ATGD0151-500, ATGD0151-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Signal Transduction

Omim

605811

NCBI Accession Number

NP_037380.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_013248.2

DNA Size

423bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.