CDK1 cDNA
The protein encoded by CDK1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Specifications
Product Name Alternative
CDC2, CDC28A, P34CDC2
Chromosomal Location
10q21.1
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
Additionnal Information
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Cell Cycle
Omim
116940
NCBI Accession Number
NP_001777.1
Species
Human
Preparation
RNA Reference
NM_001786.4
DNA Size
894bp
Vector Description
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