DYNLL1 cDNA

DYNLL1, also known as DLC8 or PIN (protein inhibitor of neuronal nitric oxide synthase), has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Binding of this protein destabilizes NOS1 (Neuronal nitric oxide synthase) dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain.

Product Specifications

Product Name Alternative

DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, PIN

Chromosomal Location

12q24.23

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGTGCGACC GAAAGGCCGT GATCAAAAAT GCGGACATGT CGGAAGAGAT GCAACAGGAC TCGGTGGAGT GCGCTACTCA GGCGCTGGAG AAATACAACA TAGAGAAGGA CATTGCGGCT CATATCAAGA AGGAATTTGA CAAGAAGTAC AATCCCACCT GGCATTGCAT CGTGGGGAGG AACTTCGGTA GTTATGTGAC ACATGAAACC AAACACTTCA TCTACTTCTA CCTGGGCCAA GTGGCCATTC TTCTGTTCAA ATCTGGTTAA

Additionnal Information

DYNLL1, DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, PIN, DYNLL1, ATGD0092-10 µg, ATGD0092-20 µg, ATGD0092-50 µg, ATGD0092-100 µg, ATGD0092-250 µg, ATGD0092-500 µg, ATGD0092-1 mg, ATGD0092-10, ATGD0092-20, ATGD0092-50, ATGD0092-100, ATGD0092-250, ATGD0092-500, ATGD0092-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Cancer

Omim

601562

NCBI Accession Number

NP_001032583.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_001037494.1

DNA Size

270bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

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